The Houston Police Department said a driver of an SUV was traveling eastbound on Pierce and crossed into the Fannin intersection around 2 a.m.
At that time, officers said a driver was speeding while heading south on Fannin and ran a red light.
Investigators said both drivers lost control, the SUV overturned and four people were killed at the scene.
Four other people were taken to hospital, where two more people died. One of the victims, a woman, was fighting for her life Saturday morning.
Police say one of the victims who died was homeless.
Eyewitness News spoke to one of his friends who was sleeping nearby and he described the moment the vehicles collided.
“Literally, it sounded like two trains crashing together. I can still hear that sound in my head. It’s scary,” he said. “I was right next to him. I just had something in my gut telling me to get up, and I got up. But that could have been me.”
Five men and a woman, including the driver at fault, were killed, according to authorities. Hayden was one of the victims, sources confirmed to ABC13. The identities of the other victims have not all been released.